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Dissociation of ATP-binding Cassette Nucleotide-binding Domain Dimers into Monomers during the Hydrolysis Cycle

ATP-binding cassette (ABC) proteins have two nucleotide-binding domains (NBDs) that work as dimers to bind and hydrolyze ATP, but the molecular mechanism of nucleotide hydrolysis is controversial. In particular, it is still unresolved whether hydrolysis leads to dissociation of the ATP-induced dimer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zoghbi, Maria E., Krishnan, Srinivasan, Altenberg, Guillermo A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340254/
https://ncbi.nlm.nih.gov/pubmed/22403405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340281
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