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ATP binding to two sites is necessary for dimerization of nucleotide-binding domains of ABC proteins
ATP binding cassette (ABC) transporters have a functional unit formed by two transmembrane domains and two nucleotide binding domains (NBDs). ATP-bound NBDs dimerize in a head-to-tail arrangement, with two nucleotides sandwiched at the dimer interface. Both NBDs contribute residues to each of the tw...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3901029/ https://ncbi.nlm.nih.gov/pubmed/24269240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.11.050 |
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