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ATP binding to two sites is necessary for dimerization of nucleotide-binding domains of ABC proteins

ATP binding cassette (ABC) transporters have a functional unit formed by two transmembrane domains and two nucleotide binding domains (NBDs). ATP-bound NBDs dimerize in a head-to-tail arrangement, with two nucleotides sandwiched at the dimer interface. Both NBDs contribute residues to each of the tw...

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Bibliografiske detaljer
Main Authors: Zoghbi, Maria E., Altenberg, Guillermo A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901029/
https://ncbi.nlm.nih.gov/pubmed/24269240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.11.050
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