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The Lipid Bilayer Modulates the Structure and Function of an ATP-binding Cassette Exporter

ATP-binding cassette exporters use the energy of ATP hydrolysis to transport substrates across membranes by switching between inward- and outward-facing conformations. Essentially all structural studies of these proteins have been performed with the proteins in detergent micelles, locked in specific...

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Pubblicato in:J Biol Chem
Autori principali: Zoghbi, Maria E., Cooper, Rebecca S., Altenberg, Guillermo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813473/
https://ncbi.nlm.nih.gov/pubmed/26725230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698498
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