Φορτώνει......
Structure of human Mad1 C-terminal domain reveals its involvement in kinetochore targeting
The spindle checkpoint prevents aneuploidy by delaying anaphase onset until all sister chromatids achieve proper microtubule attachment. The kinetochore-bound checkpoint protein complex Mad1-Mad2 promotes the conformational activation of Mad2 and serves as a catalytic engine of checkpoint signaling....
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340083/ https://ncbi.nlm.nih.gov/pubmed/22493223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118210109 |
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