Chargement en cours...

Phosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition

Regulated conformational changes of proteins are critical for cellular signal transduction. The spindle checkpoint protein Mad2 is an unusual protein with two native folds: the latent open conformer (O-Mad2) and the activated closed conformer (C-Mad2). During mitosis, cytosolic O-Mad2 binds to the M...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kim, Soonjoung, Sun, Hongbin, Ball, Haydn L., Wassmann, Katja, Luo, Xuelian, Yu, Hongtao
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993392/
https://ncbi.nlm.nih.gov/pubmed/21041666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009000107
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!