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Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1–Mad2
The spindle assembly checkpoint (SAC) arrests cells in mitosis by sensing unattached kinetochores, until all chromosomes are bi-oriented by spindle microtubules. Kinetochore accumulation of the SAC component Mad1–Mad2 is crucial for SAC activation. However, the mechanism by which Mad1–Mad2 accumulat...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4729865/ https://ncbi.nlm.nih.gov/pubmed/26743940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10151 |
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