Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism

Bacterial transpeptidase and transglycosylase on the surface are essential for cell wall synthesis, and many antibiotics have been developed to target the transpeptidase; however, the problem of antibiotic resistance has arisen and caused a major threat in bacterial infection. The transglycosylase h...

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Autors principals: Huang, Chia-Ying, Shih, Hao-Wei, Lin, Li-Ying, Tien, Yi-Wen, Cheng, Ting-Jen Rachel, Cheng, Wei-Chieh, Wong, Chi-Huey, Ma, Che
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340074/
https://ncbi.nlm.nih.gov/pubmed/22493270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203900109
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