Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism

Bacterial transpeptidase and transglycosylase on the surface are essential for cell wall synthesis, and many antibiotics have been developed to target the transpeptidase; however, the problem of antibiotic resistance has arisen and caused a major threat in bacterial infection. The transglycosylase h...

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Detalhes bibliográficos
Main Authors: Huang, Chia-Ying, Shih, Hao-Wei, Lin, Li-Ying, Tien, Yi-Wen, Cheng, Ting-Jen Rachel, Cheng, Wei-Chieh, Wong, Chi-Huey, Ma, Che
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340074/
https://ncbi.nlm.nih.gov/pubmed/22493270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203900109
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