Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli

Drug-resistant bacteria have caused serious medical problems in recent years, and the need for new antibacterial agents is undisputed. Transglycosylase, a multidomain membrane protein essential for cell wall synthesis, is an excellent target for the development of new antibiotics. Here, we determine...

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Hlavní autoři: Sung, Ming-Ta, Lai, Yen-Ting, Huang, Chia-Ying, Chou, Lien-Yang, Shih, Hao-Wei, Cheng, Wei-Chieh, Wong, Chi-Huey, Ma, Che
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Physical Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689995/
https://ncbi.nlm.nih.gov/pubmed/19458048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904030106
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