Iminosugar C-Glycoside Analogues of α-d-GlcNAc-1-Phosphate: Synthesis and Bacterial Transglycosylase Inhibition

[Image: see text] We herein describe the first synthesis of iminosugar C-glycosides of α-d-GlcNAc-1-phosphate in 10 steps starting from unprotected d-GlcNAc. A diastereoselective intramolecular iodoamination–cyclization as the key step was employed to construct the central piperidine ring of the imi...

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Библиографические подробности
Главные авторы: Hsu, Che-Hsiung, Schelwies, Mathias, Enck, Sebastian, Huang, Lin-Ya, Huang, Shih-Hsien, Chang, Yi-Fan, Cheng, Ting-Jen Rachel, Cheng, Wei-Chieh, Wong, Chi-Huey
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4168788/
https://ncbi.nlm.nih.gov/pubmed/25137529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo501340s
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