Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice

Suppression of cyclooxygenase 2 (COX-2)–derived prostacyclin (PGI(2)) is sufficient to explain most elements of the cardiovascular hazard from nonsteroidal antinflammatory drugs (NSAIDs). However, randomized trials are consistent with the emergence of cardiovascular risk during chronic dosing with N...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yu, Zhou, Crichton, Irene, Tang, Soon Yew, Hui, Yiqun, Ricciotti, Emanuela, Levin, Mark D., Lawson, John A., Puré, Ellen, FitzGerald, Garret A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340044/
https://ncbi.nlm.nih.gov/pubmed/22493243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115313109
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