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Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice

Suppression of cyclooxygenase 2 (COX-2)–derived prostacyclin (PGI(2)) is sufficient to explain most elements of the cardiovascular hazard from nonsteroidal antinflammatory drugs (NSAIDs). However, randomized trials are consistent with the emergence of cardiovascular risk during chronic dosing with N...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Zhou, Crichton, Irene, Tang, Soon Yew, Hui, Yiqun, Ricciotti, Emanuela, Levin, Mark D., Lawson, John A., Puré, Ellen, FitzGerald, Garret A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340044/
https://ncbi.nlm.nih.gov/pubmed/22493243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115313109
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