Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice

Suppression of cyclooxygenase 2 (COX-2)–derived prostacyclin (PGI(2)) is sufficient to explain most elements of the cardiovascular hazard from nonsteroidal antinflammatory drugs (NSAIDs). However, randomized trials are consistent with the emergence of cardiovascular risk during chronic dosing with N...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Yu, Zhou, Crichton, Irene, Tang, Soon Yew, Hui, Yiqun, Ricciotti, Emanuela, Levin, Mark D., Lawson, John A., Puré, Ellen, FitzGerald, Garret A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3340044/
https://ncbi.nlm.nih.gov/pubmed/22493243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115313109
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge