Intercalation of ethidium bromide into a triple-stranded oligonucleotide.

We have examined the ability of a cationic planar chromophore, ethidium bromide, to intercalate into a short, defined triple helix. Using UV absorption, fluorescence spectroscopy and a gel retardation assay we demonstrate that ethidium bromide is able to bind to a triple helix with a lower affinity...

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Main Authors: Mergny, J L, Collier, D, Rougée, M, Montenay-Garestier, T, Hélène, C
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC333910/
https://ncbi.nlm.nih.gov/pubmed/2027760
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