Intercalation of ethidium bromide into a triple-stranded oligonucleotide.
We have examined the ability of a cationic planar chromophore, ethidium bromide, to intercalate into a short, defined triple helix. Using UV absorption, fluorescence spectroscopy and a gel retardation assay we demonstrate that ethidium bromide is able to bind to a triple helix with a lower affinity...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1991
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2027760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.7.1521 |
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