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Formal Synthesis of (−)-Englerin A and Cytotoxicity Studies of Truncated Englerins

An efficient formal synthesis of (−)-englerin A (1) is reported. The target molecule is a recently isolated guaiane sesquiterpene that possesses highly potent and selective activity against renal cancer cell lines. The developed strategy proceeds in an enantioselective manner by constructing the BC...

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Hlavní autoři: Xu, Jing, Caro-Diaz, Eduardo J.E., Batova, Ayse, Sullivan, Steven D. E., Theodorakis, Emmanuel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338859/
https://ncbi.nlm.nih.gov/pubmed/22415793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/asia.201101021
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