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Formal Synthesis of (−)-Englerin A and Cytotoxicity Studies of Truncated Englerins
An efficient formal synthesis of (−)-englerin A (1) is reported. The target molecule is a recently isolated guaiane sesquiterpene that possesses highly potent and selective activity against renal cancer cell lines. The developed strategy proceeds in an enantioselective manner by constructing the BC...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3338859/ https://ncbi.nlm.nih.gov/pubmed/22415793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/asia.201101021 |
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