Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Renal cell carcinoma (RCC), the most common malignancy of the kidney, is refractory to standard therapy and has an incidence that continues to rise. Screening of plant extracts in search of new agents to treat RCC resulted in the discovery of englerin A (EA), a natural product exhibiting potent sele...

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Detalhes bibliográficos
Main Authors: Williams, Richard T, Yu, Alice L, Diccianni, Mitchell B, Theodorakis, Emmanuel A, Batova, Ayse
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765946/
https://ncbi.nlm.nih.gov/pubmed/23958461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-57
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