Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: Implications for preconditioning

BACKROUND: Reactive oxygen species (ROS) mediate the effects of anesthetic precondition to protect against ischemia and reperfusion injury, but the mechanisms of ROS generation remain unclear. In this study, we investigated if mitochondria-targeted antioxidant (mitotempol) abolishes the cardioprotec...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hirata, Naoyuki, Shim, Yon Hee, Pravdic, Danijel, Lohr, Nicole L., Pratt, Philip F., Weihrauch, Dorothee, Kersten, Judy R., Warltier, David C, Bosnjak, Zeljko J., Bienengraeber, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337729/
https://ncbi.nlm.nih.gov/pubmed/21862887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31822a2316
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