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Association of Activated c-Met with NRAS-Mutated Human Melanomas: A Possible Avenue for Targeting

Cutaneous melanomas can be divided into three mutually exclusive genetic subsets: tumors with mutated BRAF, tumors with mutated NRAS, and tumors wild type at both loci (wt/wt). Targeted therapy for melanoma has been advancing with agents directed to mutated BRAF, accounting for 50% of melanoma patie...

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מידע ביבליוגרפי
Main Authors: Chattopadhyay, Chandrani, Ellerhorst, Julie A., Ekmekcioglu, Suhendan, Greene, Victoria R., Davies, Michael A., Grimm, Elizabeth A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337366/
https://ncbi.nlm.nih.gov/pubmed/22020736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26487
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