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Tumor suppressor function of RUNX3 in breast cancer

Emerging evidence indicates that RUNX3 is a tumor suppressor in breast cancer. RUNX3 is frequently inactivated in human breast cancer cell lines and cancer samples by hemizygous deletion of the Runx3 gene, hypermethylation of the Runx3 promoter, or cytoplasmic sequestration of RUNX3 protein. Inactiv...

詳細記述

保存先:
書誌詳細
第一著者: Chen, Lin-Feng
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337355/
https://ncbi.nlm.nih.gov/pubmed/22275124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24074
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