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Gelsolin Amyloidosis: Genetics, Biochemistry, Pathology and Possible Strategies for Therapeutic Intervention

Protein misassembly into aggregate structures, including cross-β-sheet amyloid fibrils, is linked to diseases characterized by the degeneration of post-mitotic tissue. While amyloid fibril deposition in the extracellular space certainly disrupts cellular and tissue architecture late in the course of...

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Detalhes bibliográficos
Main Authors: Solomon, James P., Page, Lesley J., Balch, William E., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337338/
https://ncbi.nlm.nih.gov/pubmed/22360545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2012.661401
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