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Heparin Accelerates Gelsolin Amyloidogenesis

The chemical environment of the extracellular matrix may influence the tissue-selective deposition observed there in gelsolin amyloid disease. Previously, we have identified the proteases that generate the amyloidogenic fragments from the full length gelsolin variants, and demonstrated that heparin...

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Detalhes bibliográficos
Main Authors: Suk, Ji Young, Zhang, Fuming, Balch, William E., Linhardt, Robert J., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657342/
https://ncbi.nlm.nih.gov/pubmed/16475811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0519295
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