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Formation of gelsolin amyloid fibrils in the rough endoplasmic reticulum of skeletal muscle in the gelsolin mouse model of inclusion body myositis. Comparative analysis to human sporadic inclusion body myositis
Sporadic inclusion body myositis has a significant impact on life of elderly. Despite some similarities to other myopathies with established genetic defects little is known about mechanisms of its development and no effective treatment is available. Therefore there is a need for animal models, which...
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| Publié dans: | Ultrastruct Pathol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4461228/ https://ncbi.nlm.nih.gov/pubmed/24047347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/01913123.2013.810684 |
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