Impaired Autophagy in Sporadic Inclusion-Body Myositis and in Endoplasmic Reticulum Stress-Provoked Cultured Human Muscle Fibers

The hallmark pathologies of sporadic inclusion-body myositis (s-IBM) muscle fibers are autophagic vacuoles and accumulation of ubiquitin-positive multiprotein aggregates that contain amyloid-β or phosphorylated tau in a β-pleated sheet amyloid configuration. Endoplasmic reticulum stress (ERS) and 26...

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Detalhes bibliográficos
Main Authors: Nogalska, Anna, D'Agostino, Carla, Terracciano, Chiara, Engel, W. King, Askanas, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928970/
https://ncbi.nlm.nih.gov/pubmed/20616343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100050
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