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Inclusion Body Myositis: A Degenerative Muscle Disease Associated with Intra‐Muscle Fiber Multi‐Protein Aggregates, Proteasome Inhibition, Endoplasmic Reticulum Stress and Decreased Lysosomal Degradation

Sporadic inclusion body myositis (s‐IBM), the most common muscle disease of older persons, is of unknown cause, and there is no enduring treatment. Abnormal accumulation of intracellular multi‐protein inclusions is a characteristic feature of the s‐IBM phenotype, and as such s‐IBM can be considered...

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Bibliografiska uppgifter
I publikationen:Brain Pathol
Huvudupphovsmän: Askanas, Valerie, Engel, W. King, Nogalska, Anna
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094750/
https://ncbi.nlm.nih.gov/pubmed/19563541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00290.x
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