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Endoplasmic Reticulum Stress and Unfolded Protein Response in Inclusion Body Myositis Muscle

Proteins in the endoplasmic reticulum (ER) require an efficient system of molecular chaperones whose role is to assure their proper folding and to prevent accumulation of unfolded proteins. The response of cells to accumulation of unfolded proteins in the ER is termed “unfolded protein response” (UP...

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Detalhes bibliográficos
Main Authors: Vattemi, Gaetano, Engel, W. King, McFerrin, Janis, Askanas, Valerie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602240/
https://ncbi.nlm.nih.gov/pubmed/14695312
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