Endoplasmic Reticulum Stress and Unfolded Protein Response in Inclusion Body Myositis Muscle

Proteins in the endoplasmic reticulum (ER) require an efficient system of molecular chaperones whose role is to assure their proper folding and to prevent accumulation of unfolded proteins. The response of cells to accumulation of unfolded proteins in the ER is termed “unfolded protein response” (UP...

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Autores principales: Vattemi, Gaetano, Engel, W. King, McFerrin, Janis, Askanas, Valerie
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2004
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602240/
https://ncbi.nlm.nih.gov/pubmed/14695312
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