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Inclusion Body Myositis: A Degenerative Muscle Disease Associated with Intra‐Muscle Fiber Multi‐Protein Aggregates, Proteasome Inhibition, Endoplasmic Reticulum Stress and Decreased Lysosomal Degradation
Sporadic inclusion body myositis (s‐IBM), the most common muscle disease of older persons, is of unknown cause, and there is no enduring treatment. Abnormal accumulation of intracellular multi‐protein inclusions is a characteristic feature of the s‐IBM phenotype, and as such s‐IBM can be considered...
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| Опубликовано в: : | Brain Pathol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094750/ https://ncbi.nlm.nih.gov/pubmed/19563541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2009.00290.x |
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