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Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions
The small GTPase Ras is activated in a high proportion of human cancers. Attempts to clinically block Ras activity through pharmacological means has proven largely ineffective thus far. We employed an inducible mouse model of squamous cell carcinoma (SCC) to study the effect of Ras activation and sh...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337161/ https://ncbi.nlm.nih.gov/pubmed/22545230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.18088 |
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