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Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions
The small GTPase Ras is activated in a high proportion of human cancers. Attempts to clinically block Ras activity through pharmacological means has proven largely ineffective thus far. We employed an inducible mouse model of squamous cell carcinoma (SCC) to study the effect of Ras activation and sh...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337161/ https://ncbi.nlm.nih.gov/pubmed/22545230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.18088 |
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