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Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions

The small GTPase Ras is activated in a high proportion of human cancers. Attempts to clinically block Ras activity through pharmacological means has proven largely ineffective thus far. We employed an inducible mouse model of squamous cell carcinoma (SCC) to study the effect of Ras activation and sh...

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Autors principals: White, Andrew C., Lowry, William E.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337161/
https://ncbi.nlm.nih.gov/pubmed/22545230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.18088
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