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Defining the origins of Ras/p53-mediated squamous cell carcinoma

The precise identity of cancer cells of origin and the molecular events of tumor initiation in epidermal squamous cell carcinoma (SCC) are unknown. Here we show that malignancy potential is related to the developmental capacity of the initiating cancer cell in a genetically defined, intact, and indu...

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Detalhes bibliográficos
Main Authors: White, Andrew C., Tran, Kathy, Khuu, Joan, Dang, Christine, Cui, Yongyan, Binder, Scott W., Lowry, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088581/
https://ncbi.nlm.nih.gov/pubmed/21502519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012670108
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