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Defining the origins of Ras/p53-mediated squamous cell carcinoma

The precise identity of cancer cells of origin and the molecular events of tumor initiation in epidermal squamous cell carcinoma (SCC) are unknown. Here we show that malignancy potential is related to the developmental capacity of the initiating cancer cell in a genetically defined, intact, and indu...

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Autori principali: White, Andrew C., Tran, Kathy, Khuu, Joan, Dang, Christine, Cui, Yongyan, Binder, Scott W., Lowry, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088581/
https://ncbi.nlm.nih.gov/pubmed/21502519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012670108
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