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Resistance to echinocandins comes at a cost: The impact of FKS1 hotspot mutations on Candida albicans fitness and virulence

The emergence of Candida strains carrying FKS1 hotspot mutations associated with resistance to echinocandins is cause for concern. However, to assess the potential of such strains to spread within the community and cause lethal infection, the impact of FKS1 mutations on Candida fitness must be deter...

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Autors principals: Ben-Ami, Ronen, Kontoyiannis, Dimitrios P.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337155/
https://ncbi.nlm.nih.gov/pubmed/22286697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/viru.3.1.18886
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