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Differential contribution of dendritic cell CD1d to NKT cell-enhanced humoral immunity and CD8(+) T cell activation

CD1d-restricted type I NKT cells provide help for specific antibody production. B cells, which have captured and presented a T-dependent, antigen-derived peptide on MHC class II and CD1d-binding glycolipid α-GC on CD1d, respectively, activate Th and NKT cells to elicit B cell help. However, the role...

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Detalhes bibliográficos
Main Authors: Joshi, Sunil K., Lang, Gillian A., Devera, T. Scott, Johnson, Amy M., Kovats, Susan, Lang, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336769/
https://ncbi.nlm.nih.gov/pubmed/22331103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1111559
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