Type II NKT cells facilitate Alum-sensing and humoral immunity

Alum-based adjuvants facilitate vaccine-driven humoral immunity, but their mechanism of action remains poorly understood. Herein, we report that lack of type II NKT cells is associated with intact, mature B cells but dampened humoral immunity following immunization with Alum-adsorbed T-dependent ant...

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Detaylı Bibliyografya
Asıl Yazarlar: Shah, Hemangi B., Devera, T. Scott, Rampuria, Pragya, Lang, Gillian A., Lang, Mark L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Leukocyte Biology 2012
Konular:
Host Defense & Pathophysiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441316/
https://ncbi.nlm.nih.gov/pubmed/22798686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0412177
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