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Reduction of CD1d expression in vivo minimally affects NKT-enhanced antibody production but boosts B-cell memory
The CD1d-binding glycolipid α-galactosylceramide exerts potent adjuvant effects on T-dependent humoral immunity. The mechanism is driven by cognate interaction between CD1d-expressing B cells and TCR-expressing type I CD1d-restricted NKT cells. Thus, far positive effects of alpha-galactosylceramide...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3066037/ https://ncbi.nlm.nih.gov/pubmed/21398691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq477 |
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