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Reduction of CD1d expression in vivo minimally affects NKT-enhanced antibody production but boosts B-cell memory

The CD1d-binding glycolipid α-galactosylceramide exerts potent adjuvant effects on T-dependent humoral immunity. The mechanism is driven by cognate interaction between CD1d-expressing B cells and TCR-expressing type I CD1d-restricted NKT cells. Thus, far positive effects of alpha-galactosylceramide...

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Main Authors: Lang, Gillian A., Johnson, Amy M., Devera, T. Scott, Joshi, Sunil K., Lang, Mark L.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066037/
https://ncbi.nlm.nih.gov/pubmed/21398691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq477
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