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CD70 expression by dendritic cells plays a critical role in the immunogenicity of CD40-independent, CD4(+) T cell-dependent, licensed CD8(+) T cell responses
The stimulation of DC by CD4(+) T cells is known to condition DC to activate naïve CD8(+) T cells, predominantly via CD40-CD40L interactions. It has been proposed that a critical consequence of DC conditioning is the induction of CD70 expression. Whether and how CD70 induction contributes to CD8(+)...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Society for Leukocyte Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830127/ https://ncbi.nlm.nih.gov/pubmed/19952354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0809535 |
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