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CD70 expression by dendritic cells plays a critical role in the immunogenicity of CD40-independent, CD4(+) T cell-dependent, licensed CD8(+) T cell responses

The stimulation of DC by CD4(+) T cells is known to condition DC to activate naïve CD8(+) T cells, predominantly via CD40-CD40L interactions. It has been proposed that a critical consequence of DC conditioning is the induction of CD70 expression. Whether and how CD70 induction contributes to CD8(+)...

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Detalhes bibliográficos
Main Authors: Van Deusen, Katherine E., Rajapakse, Rohan, Bullock, Timothy N. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830127/
https://ncbi.nlm.nih.gov/pubmed/19952354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0809535
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