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Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN
The dysfunction of TAR DNA-binding protein-43 (TDP-43) is implicated in neurodegenerative diseases. However, the function of TDP-43 is not fully elucidated. Here we show that the protein level of endogenous TDP-43 in the nucleus is increased in mouse cortical neurons in the early stages, but return...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Company of Biologists
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336381/ https://ncbi.nlm.nih.gov/pubmed/22526419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.095729 |
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