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Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN

The dysfunction of TAR DNA-binding protein-43 (TDP-43) is implicated in neurodegenerative diseases. However, the function of TDP-43 is not fully elucidated. Here we show that the protein level of endogenous TDP-43 in the nucleus is increased in mouse cortical neurons in the early stages, but return...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zheng, Mei, Liao, Mingxia, Cui, Tianyuan, Tian, Honglin, Fan, Dong-Sheng, Wan, Qi
פורמט: Artigo
שפה:Inglês
יצא לאור: Company of Biologists 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3336381/
https://ncbi.nlm.nih.gov/pubmed/22526419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.095729
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