Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons

Antzeko izenburuak

• Cytoplasmic TDP-43 de-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death
  nork: Gasset-Rosa, Fatima, et al.
  Argitaratua: (2019)
• Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin
  nork: Amlie-Wolf, Alexandre, et al.
  Argitaratua: (2015)
• ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
  nork: Arnold, Eveline S., et al.
  Argitaratua: (2013)
• Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration
  nork: Lee, Edward B., et al.
  Argitaratua: (2011)
• TDP-43 regulates transcription at protein-coding genes and Alu retrotransposons
  nork: Morera, Andrés A., et al.
  Argitaratua: (2019)