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Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome
Protein glycosylation is a ubiquitous modification that affects the structure and function of proteins. Our recent genome wide association study identified transcription factor HNF1A as an important regulator of plasma protein glycosylation. To evaluate the potential impact of epigenetic regulation...
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| 主要な著者: | , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335910/ https://ncbi.nlm.nih.gov/pubmed/22395466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.2.18918 |
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