Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome

Protein glycosylation is a ubiquitous modification that affects the structure and function of proteins. Our recent genome wide association study identified transcription factor HNF1A as an important regulator of plasma protein glycosylation. To evaluate the potential impact of epigenetic regulation...

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Bibliografski detalji
Glavni autori: Zoldoš, Vlatka, Horvat, Tomislav, Novokmet, Mislav, Cuenin, Cyrille, Mužinić, Ana, Pučić, Maja, Huffman, Jennifer E, Gornik, Olga, Polašek, Ozren, Campbell, Harry, Hayward, Caroline, Wright, Alan F, Rudan, Igor, Owen, Katharine, McCarthy, Mark I, Herceg, Zdenko, Lauc, Gordan
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335910/
https://ncbi.nlm.nih.gov/pubmed/22395466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.2.18918
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