Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome

Protein glycosylation is a ubiquitous modification that affects the structure and function of proteins. Our recent genome wide association study identified transcription factor HNF1A as an important regulator of plasma protein glycosylation. To evaluate the potential impact of epigenetic regulation...

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Detaylı Bibliyografya
Asıl Yazarlar: Zoldoš, Vlatka, Horvat, Tomislav, Novokmet, Mislav, Cuenin, Cyrille, Mužinić, Ana, Pučić, Maja, Huffman, Jennifer E, Gornik, Olga, Polašek, Ozren, Campbell, Harry, Hayward, Caroline, Wright, Alan F, Rudan, Igor, Owen, Katharine, McCarthy, Mark I, Herceg, Zdenko, Lauc, Gordan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2012
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335910/
https://ncbi.nlm.nih.gov/pubmed/22395466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.2.18918
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