Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome

Protein glycosylation is a ubiquitous modification that affects the structure and function of proteins. Our recent genome wide association study identified transcription factor HNF1A as an important regulator of plasma protein glycosylation. To evaluate the potential impact of epigenetic regulation...

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Bibliografische gegevens
Hoofdauteurs: Zoldoš, Vlatka, Horvat, Tomislav, Novokmet, Mislav, Cuenin, Cyrille, Mužinić, Ana, Pučić, Maja, Huffman, Jennifer E, Gornik, Olga, Polašek, Ozren, Campbell, Harry, Hayward, Caroline, Wright, Alan F, Rudan, Igor, Owen, Katharine, McCarthy, Mark I, Herceg, Zdenko, Lauc, Gordan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2012
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335910/
https://ncbi.nlm.nih.gov/pubmed/22395466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.2.18918
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