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Designing photoswitchable peptides using the AsLOV2 domain
Photocontrol of functional peptides is a powerful tool for spatial and temporal control of cell signaling events. We show that the genetically encoded light-sensitive LOV2 domain of Avena Sativa phototropin 1 (AsLOV2) can be used to reversibly photomodulate the affinity of peptides for their binding...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334866/ https://ncbi.nlm.nih.gov/pubmed/22520757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.02.006 |
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