Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation

Flavin mononucleotide (FMN) belongs to the group of very efficient endogenous photosensitizers producing singlet oxygen, (1)O(2), but with limited ability to be targeted. On the other hand, in genetically-encoded photosensitizers, which can be targeted by means of various tags, the efficiency of FMN...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Petrenčáková, Martina, Filandr, František, Hovan, Andrej, Yassaghi, Ghazaleh, Man, Petr, Kožár, Tibor, Schwer, Marc-Simon, Jancura, Daniel, Plückthun, Andreas, Novák, Petr, Miškovský, Pavol, Bánó, Gregor, Sedlák, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058016/
https://ncbi.nlm.nih.gov/pubmed/32139757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60861-2
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