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Rationally improving LOV domain–based photoswitches

Genetically-encoded protein photosensors, including the LOV (light, oxygen, voltage) domain, are promising tools for engineering optical control of cellular behavior. We are only beginning to understand how to couple these light detectors to effectors of choice. We report a method that increases the...

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Detalhes bibliográficos
Main Authors: Strickland, Devin, Yao, Xiaolan, Gawlak, Grzegorz, Rosen, Michael K., Gardner, Kevin H., Sosnick, Tobin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914111/
https://ncbi.nlm.nih.gov/pubmed/20562867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1473
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