Rationally improving LOV domain–based photoswitches

Genetically-encoded protein photosensors, including the LOV (light, oxygen, voltage) domain, are promising tools for engineering optical control of cellular behavior. We are only beginning to understand how to couple these light detectors to effectors of choice. We report a method that increases the...

Full description

Saved in:
Bibliographic Details
Main Authors: Strickland, Devin, Yao, Xiaolan, Gawlak, Grzegorz, Rosen, Michael K., Gardner, Kevin H., Sosnick, Tobin R.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914111/
https://ncbi.nlm.nih.gov/pubmed/20562867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1473
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items