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Microparticles as biological vectors of activated protein C treatment in sepsis
Activated protein C (APC), a physiological coagulation inhibitor, has been shown to reduce mortality in patients with severe sepsis. APC exerts pleiotropic cytoprotection by a mechanism that requires its interaction with endothelial cell protein C receptor and protease-activated receptor-1 on target...
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| Formato: | Artigo |
| Idioma: | Inglês |
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BioMed Central
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334738/ https://ncbi.nlm.nih.gov/pubmed/22017971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10416 |
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