Microparticles Carrying Sonic Hedgehog Favor Neovascularization through the Activation of Nitric Oxide Pathway in Mice

BACKGROUND: Microparticles (MPs) are vesicles released from plasma membrane upon cell activation and during apoptosis. Human T lymphocytes undergoing activation and apoptosis generate MPs bearing morphogen Shh (MPs(Shh+)) that are able to regulate in vitro angiogenesis. METHODOLOGY/PRINCIPAL FINDING...

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Detalhes bibliográficos
Main Authors: Benameur, Tarek, Soleti, Raffaella, Porro, Chiara, Andriantsitohaina, Ramaroson, Martínez, Maria Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938335/
https://ncbi.nlm.nih.gov/pubmed/20856928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012688
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